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Absorption and Drug Development: Solubility, Permeability and Charge State

Name: Absorption and Drug Development: Solubility, Permeability and Charge State
ISBN: 9780471423652

Alex Avdeef

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Of the hundreds of thousands of compounds synthesized each year, most have almost no chance of becoming drugs. This problem exists because most molecules lack the drug-like properties necessary to enable them to be effective in vivo. To address this issue, Alex Avdeef's Absorption and Drug Development shows the reader how to examine a compound's pharmaceutical properties, emphasizing oral absorption. This book explains the different physicochemical methods currently used to analyze drug candidates and how to interpret these methods. Also included are physicochemical data for over 200 commercial drugs. With over 600 references and 100 drawings, this book is an excellent resource for the practical pharmaceutical chemist and those seeking a better understanding of physicochemical measurements.

Категории:

Medicine

Год:

2003

Издание:

Издательство:

Wiley-Interscience

Язык:

english

Страницы:

307

ISBN 10: