Computational Design of Membrane Proteins
Irina S. Moreira, Miguel Machuqueiro, Joana Mourão
This volume provides an overview of the current successes as well as pitfalls and caveats that are hindering the design of membrane proteins. Divided into six parts, chapters detail membrane transporter, FoldX force field, protein stability, G-Protein Coupled Receptors (GPCR) structures, transmembrane helices, membrane molecular dynamics (MD) simulations, pH-dependent protonation states, membrane permeability, and passive transport. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Design of Membrane Proteins aims to ensure successful results in the further study of this vital field.
Год:
2021
Издание:
1st
Издательство:
Humana
Язык:
english
Страницы:
290
ISBN 10:
1071614673
ISBN 13:
9781071614679
Файл:
PDF, 8.03 MB
IPFS:
,
english, 2021